Journal article
Which clinical research questions are the most important? Development and preliminary validation of the Australia & New Zealand Musculoskeletal (ANZMUSC) Clinical Trials Network Research Question Importance Tool (ANZMUSC-RQIT)
WJ Taylor, R Willink, DA O Connor, V Patel, A Bourne, IA Harris, SL Whittle, B Richards, O Clavisi, S Green, RS Hinman, CG Maher, A Cahill, A McPherson, C Hewson, SE May, B Walker, PC Robinson, D Ghersi, J Fitzpatrick Show all
Plos One | Published : 2023
Abstract
High quality clinical research that addresses important questions requires significant resources. In resource-constrained environments, projects will therefore need to be prioritized. The Australia and New Zealand Musculoskeletal (ANZMUSC) Clinical Trials Network aimed to develop a stakeholder-based, transparent, easily implementable tool that provides a score for the importance of a research question which could be used to rank research projects in order of importance. Methods Using a mixed-methods, multi-stage approach that included a Delphi survey, consensus workshop, inter-rater reliability testing, validity testing and calibration using a discrete-choice methodology, the Research Questi..
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Grants
Awarded by Australia and New Zealand Musculoskeletal Clinical Trials Network
Funding Acknowledgements
This study was funded by the Australian National Health and Medical Research Council (NHMRC) Australia & New Zealand Musculoskeletal (ANZMUSC) Clinical Trials Network Centre of Research Excellence (APP1134856). RB is supported by an NHMRC Investigator Fellowship (APP1194483). RSH is supported by an NHMRC Senior Research Fellowship (APP1154217). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.